ISSN: 1305-3876
Hakkında: Özel sayılar şeklinde yayınlanır.
|
|
|
The Physiology Of Sleep
Dr. İbrahim Hakkı BORA,a Dr. Aylin BİCANa
aNöroloji AD, Uludağ Üniversitesi Tıp Fakültesi, BURSA
Sleep is primarly the function of the brain and is an active multidisciplinary process.
Normaly sleep has two stages: Sleep in which there are no rapildy eye movements (NREM) and sleep in which there are rapidly eye movements (REM). These sleep stages are determined which neurophysical parametres such as: Electroencephalogram (EEG), electrooculography (EOG) and electromyography (EMG).
NREM sleep is divided in to four stages according to sleep EEG patterns. NREM are called 1-2 light sleep and NREM 3-4 are called deep sleep. Each sleep cycle lasts about 90-120 minutes.Sleep cycle is repeted 3-6 times during night. Major regions which are responsible for weakness are Reticulary formasion, basal forebrain, locus seruleus, dorsal raphe and posterior hypothalamus, dopaminergic A 11 region and responsible neurotransmitter are asetylcholine, noradreneline, serotonine. Major regions which are responsible for sleep are ventrolateral preoptic region, cholinergic laterodorsal tegmental nucleus and pedinculopontine tegmental nucleus which are especialy responsible for REM sleep and responsible neurotransmitter are GABA and asetylcholine.Keywords: REM, NREM, acetylcholine, serotonineTurkiye Klinikleri J Surg Med Sci 2007, 3(23):1-6
|
|
|
|
|
